2020

Harden S., Zhou J., Maria Diniz-da-Costa, Lucas E., Cui L., Murakami K., Fang J., Chen Q., Brosens J. J., Lee Y.H.. Exometabolomic analysis of decidualizing human endometrial stromal and perivascular cells. bioRxiv 2020.08.06.221119; DOI: 10.1101/2020.08.06.221119 

​

2020

A pilot study of discovery and validation of peritoneal endometriosis biomarkers in peritoneal fluid and serum. Loy S. L., Zhou J., Cui L., Tan T.Y., Chern B.S.M., Chan J.C.K.Y., Lee Y.H. MedRxiv 2020.10.13.20211789; DOI: 10.1101/2020.10.13.20211789. 

​

2020

Zhou J., Chern B. S. M., Barton-Smith P., Yang X. J., …. Chan J.K.Y. & Lee Y.H. Peritoneal fluid cytokines reveal new signatures of endometriosis sub-phenotypes. International Journal of Molecular Sciences. 21, 3515. 

​

2019

Mackens S., Santos-Ribeiro S., Racca A., D. Daneels, A. Koch, Essahib W., Verpoest W. Bourgain Van Riet C., Tournaye H., Brosens J. J., Lee Y. H., Blockeel C., Van de Velde H. The proliferative phase endometrium in IVF/ICSI: an in-cycle molecular analysis predictive of the outcome following fresh embryo transfer. Human Reproduction. 35, 130–144. DOI: 10.1093/humrep/dez218

​

2019

Chan K. R, Gan S., …, Lee Y.H., Low J. G. H. & Ooi E.E. Elevated ER stress response and metabolic feedback increases susceptibility to symptomatic flaviviral infection. Nature Medicine. 25, 1218–1224.

​

2019

Bidet K., Ho V., … de Sessions P. F., Lee Y.H., Hibberd M. L., Ooi E.E. Katja Fink, & Chen J. Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity. NPJ Vaccines. 4, 27.

​

2019

Zhu L., Zhou J., Cui L., & Lee Y.H. Retention time bracketing for targeted sphingolipidomics by liquid-chromatography-tandem mass spectrometry. Bioanalysis. 11, (3) 

​

2018

Beyer S., Koch M., Lee Y.H., Jung F., Blocki A. An in vitro model of angiogenesis during wound healing provides insights into the complex role of cells and factors in the inflammatory and proliferation phase. International Journal of Molecular Sciences. 19, 2913.

​

2018

Lee Y.H.†, Yang X. J., Allen J. C., Tan C. S., Chern B. S. M., Tan T. Y., Tan H. H., C. N. Z., & Chan J.K.Y. Elevated peritoneal fluid ceramides in human endometriosis-associated infertility and their effects on mouse oocyte maturation. Fertility and Sterility. 110, 767–777.e5.  Editorial commentary.

​

2018

Cui L., Lu H. & Lee Y.H. Challenges and emergent solutions for LC-MS/MS based untargeted metabolomics. Mass Spectrometry Reviews. 37, 772-792. 

​

2018

Cui L., Pang J, Lee Y.H., Ooi EE, Ong CN, Leo YS & Tannenbaum S. R. Serum Metabolome Changes in Adult Patients with Severe Dengue in the Critical and Recovery Phases of Dengue Infection. PLOS Neglected Tropical Diseases. 12(1): e0006217

​

2018

Wimalachandra D., Zhu L., Tan E., Asada H. H., Chan J.K.Y & Lee Y.H. Long-chain glucosylceramides crosstalk with LYN mediates endometrial cell migration. BBA- Molecular and Cell Biology of Lipids. 1863: 71-80. PMID: 29050963

​

2017 

Brighton P.J., Maruyama Y., Fishwick K., …, Lee Y.H., Satoru Takeda, Ott S., Hemberger M., Quenby S., Brosens J. J. Clearance of senescent decidual cells by uterine natural killer cells drives endometrial remodeling during the window of implantation. eLife. 6: e31274

​

2017

Cui L., Fang J., Ooi E.E., and Lee Y.H. Serial Metabolome Changes in a Prospective Cohort of Subjects with Influenza Viral Infection and Comparison with Dengue Fever. Journal of Proteome Research. 16: 2614-2622.PMID: 28560878

​

2017

McGovern N., …Lee Y. H.,…, Chan J. K. Y. & Ginhoux F. Human fetal dendritic cells promote pre-natal T cell immune-suppression through Arginase 2 activity. Nature. 546, 662–666.  

​

2017

Cui L , Hou J, Fang J, Lee YH, Costa VV, Wong LH, Chen Q, Ooi EE, Tannenbaum SR, Chen J, Ong CN. Serum Metabolomics Investigation of Humanized Mouse Model with Dengue Infection. Journal of Virology. JVI.00386-17. IF: 4.606 PMID: 28468882.

​

2017

Durairaj R. R. P., Aberkane A., Polanski L., Maruyama Y., Baumgarten M., Lucas E., Quenby S., Chan J. K. Y., Fenning N. R., Brosens J. J., Van de Velde H. & Lee Y.H. Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure. Molecular Human Reproduction. 23: 478–487. PMID: 28402555

​

2016

Lee Y. H.‡, Leong W-Y & Wilder-Smith A. Markers of dengue severity: Systematic Review of cytokines, chemokines and growth factors. Journal of General Virology. 97: 3103-3119.  ‡Corresponding author

​

2016

Chan K. R., Wang X., Saron W. A. A. Saron, Gan E. S., Tan H. C., Mok D. Z. L., Lee Y. H., Cui L., Wijaya Limin, Ghosh S, Cheung Y. B., Tannenbaum S. R., Abraham S. N., St John A. L., Low J. G. H., Ooi E. E. Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity. Nature Microbiology. 1, 16164. PMID: 27642668

​

2016

Lee Y. H.*,‡, Cui L.*, Fang J., Chern S. M., Tan H. H.& Chan J. K. Y. Limited systemic inflammation in endometriosis – a targeted ‘omics study. Scientific Reports. 6, 26117. PMID: 27193963 

*Co-authors, ‡Corresponding author

​

2016

Cui L.*, Zheng D.*, Lee Y.H.*, Tze Khee Chan, Budigi Y., Ho E. W, Chen J. Z., Tannenbaum S. R. & Ong C. N. Metabolomics Investigation Reveals Metabolite Mediators Associated with Acute Lung Injury and Repair in a Murine Model of Influenza Pneumonia. Scientific Reports. 6, 26076. PMID: 27188343 

*Co-authors

​

2016

Cui L.*, Lee Y.H.*, Thein T-L, Fang J., Ooi E. E., Leo Y-S, Ong C. N. & Tannenbaum S.R. Serum metabolomics reveals serotonin as a unique predictor of severe dengue in the early phase of Dengue Fever. PLOS Neglected Tropical Diseases. 10 (4), e0004607. PMID: 27055163.

*Co-authors

​

2015

Lucas E. S., Dyer N. P., Murakami K., Lee Y. H., Chan Y-W., Grimaldi G., Muter J., Brighton P. J., Moore J. D., Patel G., Chan J. K. Y., Takeda S., Lam E. W-F, Quenby S., Ott S. & Brosens J. J. Loss of Endometrial Plasticity in Recurrent Pregnancy Loss. Stem Cells. 34 (2), 346-56.  PMID: 26418742

​

2015

Nie, W.N., Yan, L.Y., Lee, Y. H*., Guha, C*., Kurland, I. J*., and Lu, H.T.* . Advanced mass spectrometry based multiple omics technologies to exploring the pathogenesis of hepatocellular carcinoma. Mass Spectrometry Reviews. 35, 331-349. PMID: 24890331. 

*Corresponding authors

​

2014

Murakami K., Lee Y. H, Lucas E. S., Chan Y-W, Durairaj R. P., Takeda S., Moore J. D., Tan B. K., Quenby S., Chan K. Y. J., Gargett C. E. & Brosens J. J. Decidualization induces a secretome switch in the perivascular niche cells of the human endometrium. Endocrinology. 155(11), 4542-4553. PMID: 25116707. 

​

2014

Lee Y.H., Tan C.W., Venkatranam A., Cui L., Loh S.F., Griffith L, Tannenbaum S.R., Chan K. Y. J., Targeted sphingolipidomics implicates dysregulated glucosylceramide levels in endometriosis. Journal of Clinical Endocrinology and Metabolism. 99 (10), E1913–E1921. PMID: 24960545. 

​

2014

Tan C.W., Lee Y.H., Tan H. H., Lau M.S.K., Choolani, M., Griffith, L., Chan K.Y. CD26/DPPIV Downregulation in Endometrial Stromal Cell Migration in Endometriosis. Fertility and Sterility. 102 (1), 167-177. PMID: 24825423. 

​

2013

Molecular Biomarkers at the Interface of Basic and Clinical Dengue Research. Lee Y.H. †, Ooi E.E. Annals Academy of Medicine. 42 (11), 608-610. PMID: 24356658

†Corresponding author

​

2013

Cui L.*, Lee Y.H.*, Budigi Y., Xu F., Lu K., Ooi E.E., Tannenbaum S.R., Ong C.N. Serum Metabolome Changes in Adult Patients with Primary Dengue Infection. PLOS Neglected Tropical Diseases. 7(8): e2373. PMID: 23967362. 

*Co-authors. Featured in MDLinx.com

​

2013

Lee Y.H.†, Goh W.W., Ng C.K., Raida M., Wong L., Lin Q.S., Boelsterli  U.A., Chung M.C.M. Integrative toxicoproteomics implicates impaired mitochondrial gluthathione import as off-target effect of troglitazone. Journal of Proteome Research.12, 2933 – 2945. PMID: 23659346 

†Co-corresponding author

​

2012

Goh W.W., Lee Y.H., Ramdzan Z.M., Chung M.C.M, Wong L., Sergot M.J. A network-based maximum link approach towards MS identifies potentially important roles for undetected ARRB1/2 and ACTB in liver cancer progression. International journal of bioinformatics research and applications. 8, 155-70. PMID: 22961449

​

2012

Dong H., Chang D.C., Hua M.H., Lim S.P., Chionh Y.H., Hia F., Lee Y.H., Kukkaro P., Lok S.M., Dedon P.C. and Shi P.Y. 2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase. PLoS Pathogens. 8, e1002642. PMID: 22496660 

​

2012

Tan H. T., Lee Y.H. and Chung M. C. M. Cancer proteomics. Mass Spectrometry Reviews. 31, 583–605. PMID: 22422534 

​

2012

Goh W.W., Lee Y.H., Ramdzan Z.M., Sergot M.J., Chung M.C.M. and Wong L. Proteomics signature profiling (PSP): a novel contextualization approach for cancer proteomics. Journal of Proteome Research. 11, 1571-81. PMID: 22243476 

​

2011

Goh W.W.*, Lee Y.H..*, Zubaidah R.M., Jin J., Dong D., Lin, Q., Chung M. C. M.and Wong L. Network-based pipeline for analyzing MS data- an application towards liver cancer. Journal of Proteome Research. 10, 2261-72. PMID: 21410269 

*Co-authors.

​

2010

Lee Y.H., Tan H.T., Chung M.C.M. Subcellular fractionation methods and strategies for proteomics. Proteomics. 10, 3935-56. PMID:21080488 

​

2009

Lee Y.H., Lin, Q., Boelsterli, U.A. and Chung, M.C.M. The Sod2 mutant mouse as a model for oxidative stress: A functional proteomics perspective. Mass Spectrometry Reviews. 29, 179– 196. PMID: 19294730 

​

2008

Lee Y.H., Chung M.C.M., Lin Q. and Boelsterli U.A. Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/- Mice: Two-stage Oxidative Injury. Toxicology and Applied Pharmacology. 231, 43-51. PMID: 18495193

​

2008

Lee Y.H., Boelsterli U.A. Lin Q. and Chung M.C.M. Proteomics profiling of hepatic mitochondria in heterozygous Sod2+/- mice, an animal model of discreet mitochondrial oxidative stress. Proteomics 8, 555-568. PMID: 18232058 (Cover article).